AnnonaSense CLR™, derived from the exotic Annona cherimola fruit, offers formulators a multi-faceted approach to skin wellness by targeting the endocannabinoid system via CB2 receptor activation. This unique mechanism not only mitigates inflammation and stress markers like TRPV1, Histamine, and TNF⍺, but also down-regulates IL-31RA expression, making it a comprehensive ingredient for reducing skin sensitivity and itch. Its adaptogenic properties…
Neurocosmetics
Each ingredient is a stroke of brilliance in your brand’s story.
Discover, create, and redefine beauty with our ingredients as your canvas.
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We’ve curated a selection of ingredients available in low minimums—so you can create without overcommitting.
DandErase™
DandErase™ is a natural, microbiome-friendly anti-dandruff solution powered by bioactive compounds from Crocus sativus L (saffron flower). Developed through green fractionation and NaDES technology, it effectively targets Malassezia, the primary cause of dandruff, while maintaining scalp microbiome balance. DandErase™ provides clinically proven anti-inflammatory, anti-itch, and scalp barrier-restoring benefits, delivering results comparable to leading anti-dandruff actives without disrupting the scalp’s natural…
Manufacturer: Givaudan Active Beauty
ViewG+C Complex CLR™
G+C Complex CLR™ offers a multifaceted solution for skin aging based on nearly half a century of scientific insight into the effects of Bifida Ferment Lysate. Specifically engineered for formulators seeking to target the detrimental effects of UV exposure, this ingredient reverses DNA damage, mitigates immunosuppression, and regulates the skin cells’ circadian rhythm, making it a one-stop solution for age-defying…
Manufacturer: CLR Berlin
ViewGlycuron™ 2.78
Glycuron™ 2.78 is a marine-derived exopolysaccharide that promotes both skin and emotional well-being by leveraging the brain-skin connection. It enhances skin cell renewal, boosts hydration, and smooths texture, while also improving self-esteem and reducing stress by modulating happiness pathways, including dopamine and β-endorphin release. With neuroprotective effects against chronic stress, Glycuron™ 2.78 offers a unique combination of physical and emotional…
Manufacturer: Seqens
ViewNeuroglow™
Neuroglow™, by boosting melanin and wellbeing molecules like beta-endorphin, vitamin D and oxytocin, mimics all the good properties from the sun. Neuroglow™ is the ideal active ingredient to provide a quick and efficient solution to give the skin a healthy glow, while uplifting mood and positive emotions.
Manufacturer: Givaudan Active Beauty
ViewNeurophroline®
Neurophroline®, derived from the indigenous Indian plant wild indigo, is a powerful cosmetic ingredient renowned in Ayurvedic tradition for its skin benefits. This innovative ingredient effectively reduces cortisol production in skin cells, triggers the release of natural calming neuropeptides to improve mood, and visibly enhances skin tone within a mere two weeks, making it an ideal choice for controlling skin…
Manufacturer: Givaudan Active Beauty
ViewNutrasphere™
Nutrasphere™ is a concentrated deep sea mineral extract in free ion form, rich in magnesium, trace elements, and electrolytes. Designed for rapid skin absorption, it offers formulators a natural, water-soluble solution for enhancing cellular energy, supporting skin regeneration, and improving visible skin health without the use of synthetics or fillers. Backed by over eight years of clinical research, Nutrasphere™ provides…
Manufacturer: Oriel
ViewPatchoul’Up™
PatchoulíUp™ is a sustainable active ingredient derived from upcycled patchouli leaves in Indonesia. This eco-friendly marvel not only rebalances sebum production but also effectively eliminates dry flakes while normalizing the scalp microbiome for a holistic sense of well-being. It alleviates itching, hydrates, and soothes the scalp, making it a perfect choice for a wide range of hair care products, from…
Manufacturer: Givaudan Active Beauty
ViewSensityl™
Derived from microalgae, Sensityl™ offers exceptional benefits for cosmetic formulations. It regulates inflamm’ageing, reducing IL-8 levels by up to 26% and decreasing immune cell recruitment by 33%. Additionally, it alleviates pain sensations (-18% TRPV1 receptor expression), enhances skin’s antibacterial defenses (up to +71% fl-Defensin 2), and positively uplifts consumers’ moods, making it ideal for products like everyday creams, feel-good lotions,…
Manufacturer: Givaudan Active Beauty
ViewSilybidiol™
Silybidiol™ is the first globally compliant alternative to the iconic CBD (Cannabidiol) molecule. Designed to combat the harmful effects of urban photo-pollution and promote skin health, Silybidiol™ is extracted from the fruit of the milk thistle with Green Fractionation. It offers a new, holistic approach to aging, leveraging the emerging concept of OxInflammation, the vicious cycle connecting oxidative stress and…
Manufacturer: Givaudan Active Beauty
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