VEGAN DDS PDRN

Rice-Derived PDRN for Targeted Skin Regeneration

INCI Name: Aqua (and) Mannitol (and) Phosphatidylcholine (and) Glycerin (and) Polyglyceryl-10 Laurate (and) Cetyl Alcohol (and) Potassium Sorbate (and) Sodium Benzoate (and) Citric Acid (and) 1,2-Hexanediol (and) Cetrimonium Chloride (and) Sodium DNA (and) Sodium Phytate
Solubility: Compatible with water-based formulations, oil-in-water emulsions, water-in-oil emulsions, gels, and serums. Add to the aqueous phase or during the final manufacturing stage. Formal solubility classification is not specified.
Preservation: Potassium Sorbate (0.50–0.70%), Sodium Benzoate (0.50–0.70%), 1,2-Hexanediol (0.10–0.16%).
Global & Consumer Certifications: egan Certified, RSPO Mass Balance Certified (specified palm-derived raw materials)
Benefits: Protects against UV-A-induced oxidative protein damage. | Helps preserve collagen III levels under UV-A stress. | Supports mitochondrial function and cellular energy availability. | Helps maintain cellular proteostasis under oxidative stress. | Supports skin regeneration and recovery processes. | Protects PDRN fragments through nanovesicular delivery. | Supports targeted delivery into viable epidermal layers. | Helps reduce premature enzymatic degradation of PDRN. | Supports progressive active release and formulation compatibility. | Offers a vegan, rice-derived alternative to animal-derived PDRN.
Applications: Facial serums, Anti-aging creams, Regenerating creams, Gel-creams, Toners, Facial essences, Skin booster ampoules, Intensive treatments, Facial mists, Balm sticks, Overnight masks, Rinse-off facial masks, Professional skincare treatments

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VEGAN DDS PDRN is a rice-derived polydeoxyribonucleotide (PDRN) active encapsulated in INdermal’s Vegan Deep Delivery System (DDS) to protect DNA fragments and support targeted delivery into the viable epidermis. Designed for regenerative skincare formulations, it helps protect against UV-induced oxidative damage, preserve collagen III levels, support mitochondrial function, and maintain cellular energy availability. Ex vivo testing at a 5% use level demonstrated 71% protection against oxidative protein damage, 94% recovery of collagen III levels, and 55% protection of mitochondrial capacity under UV-A stress. Its nanovesicular delivery technology supports active stability, formulation compatibility, and progressive release, making it suitable for serums, creams, masks, and other skin longevity applications. Vegan certified and 98.8% naturally derived, it provides a plant-based alternative to conventional animal-derived PDRN.

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