A Powerful Acne Genesis Repressor
INCI Name: Hydrogenated Ethylhexyl Olivate, Passiflora Edulis Seed Oil, Cannabis Sativa Seed Oil, Pavlova Lutheri Extract
Solubility: Liposoluble
Preservation: none
Global & Consumer Certifications: ECOCERT/COSMOS approved, Palm Oil free, Vegan suitable, China approved
Benefits: Fights against inflammation / lipid synthesis dysfunction / skin disorders such as acne vulgaris, Modules the activity of Forkhead Box O1 (FoxO1) protein repressing the key genes of acne, Inhibits acne pathogensis and inflammation / hyperkeratosis / overproduction of lipids, Significantly increases the quantity of FoxO1 proteins by +32% in the nuclei of the cells at only 2% of use, Regulates FoxO1 nuclear concentration leading to a repression of genes involved in acne pathogenesis, If efficient in both acne related to puberty and hormones / acne related to stress and dietary habits, After 2 months in a creams has an excellent beneficial impact on acne and reduces: area of acne lesions by -23.7% / perimeter of acne lesions by -26.2% / height of acne lesions by -15% / number of acne lesions by 20.7%
Applications: Acne treatments and creams

Manufactured by:

Natura-Tec SeaPassion™ is an innovative cosmetic ingredient hailing from a sustainable blend of Pavlova Lutheri microalgae, passion fruit oil, and hemp seed oil, each meticulously chosen for their unique skin benefits. Leveraging the power of microalgae rich in Omega-3, long-chain EPA, and DHA fatty acids, it fortifies the skin’s natural barrier and mitigates inflammation. Additionally, its unique blend offers a high ratio of essential Omega-6 and Omega-3 fatty acids, which not only balance sebum production but also effectively inhibit the activity of the Forkhead Box O1 (FoxO1) protein, a critical regulator in acne pathogenesis. Rigorous ex-vivo and in-vivo tests confirm its efficacy in significantly reducing various metrics related to acne lesions, making it a compelling choice for formulations targeting acne caused by various factors such as puberty, hormones, stress, and diet.


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